发明名称 METHOD FOR PHOTODYNAMIC THERAPY OF NEWLY FORMED CORNEAL VESSELS
摘要 FIELD: medicine, ophthalmology. ^ SUBSTANCE: it is necessary to conduct scanning laser impulse irradiation of newly formed corneal vessels with scattering light bundle for about 5-10 min at applying the following parameters: wave length 890-900 nm, irradiation power 1-5 W in impulse, the frequency of impulses 140-160 Hz and impulse duration 50-300 nsec. Then it is necessary to introduce 0.1-1%-aqueous solution of photosensitizer of khlorin type taken out of the group of photolon, radakhlorin or photoditasin, at the dosage of about 0.8-1.1 mg/kg. Then one should perform exposition of newly formed corneal vessels without light access for about 15-20 min. Then it is necessary to apply the gel based upon hyaluronic acid viscoelastic onto corneal surface, this gel should be chosen out of the group of chealon, viscoate or hyatulon and, moreover, it is important to locate a laser light-scattering device upon corneal surface. Laser irradiation of newly formed corneal vessels should be fulfilled with scattered laser radiation at the density of laser radiation energy being 30-60 J/sq. cm. The innovation provides high efficiency in destructing newly formed corneal vessels followed by technique of optico-reconstructive keratoplasty. ^ EFFECT: higher efficiency of photodynamic therapy. ^ 1 cl, 2 ex
申请公布号 RU2288684(C2) 申请公布日期 2006.12.10
申请号 RU20050103271 申请日期 2005.02.09
申请人 GOSUDARSTVENNOE UCHREZHDENIE MEZHOTRASLEVOJ NAUCHNO-TEKHNICHESKIJ KOMPLEKS "MIKROKHIRURGIJA GLAZA" IM. AKAD. S.N. FEDOROVA MINISTERSTVA ZDRAVOOKHRANENIJA RF 发明人 BELYJ JURIJ ALEKSANDROVICH;TERESHCHENKO ALEKSANDR VLADIMIROVICH;KAPLAN MIKHAIL ALEKSANDROVICH;VOLODIN PAVEL L'VOVICH;NOVIKOV SERGEJ VIKTOROVICH
分类号 A61F9/008;A61N5/067 主分类号 A61F9/008
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