发明名称 AROMATIC COMPOUNDS
摘要 The present invention provides a novel compound, which has an excellent effect of suppressing the generation of collagen and less side effects, with being excellent in terms of safety. The compound of the present invention is represented by the following general formula (1): [wherein X<SUB>1</SUB> represents a nitrogen atom or a group -CH=; R<SUP>1</SUP> represents a group -Z-R<SUP>6</SUP>, wherein Z represents a group -CO-, a group -CH(OH)-, or the like, and R<SUP>6</SUP> represents a 5- to 15-membered monocyclic, dicyclic, or tricyclic, saturated or unsaturated heterocyclic group having 1 to 4 nitrogen atoms, oxygen atoms, or sulfur atoms; R<SUP>2</SUP> represents a hydrogen atom, a halogen atom or a lower alkylene group; Y represents a group -O-, a group -CO-, a group -CH(OH)-, a lower alkylene group, or the like; and (A) represents a group or the like, wherein R<SUP>3</SUP> represents a hydrogen atom, a lower alkoxy group, or the like, p represents 1 or 2, and R<SUP>4</SUP> represents an imidazolyl lower alkyl group or the like.
申请公布号 WO2006014012(A3) 申请公布日期 2006.12.07
申请号 WO2005JP14611 申请日期 2005.08.03
申请人 OTSUKA PHARMACEUTICAL CO., LTD.;FUKUSHIMA, TAE;MATSUMURA, SHUJI;TAKEMURA, NORIAKI;SATOU, HIDEAKI;ITO, NOBUAKI;SHITSUTA, TAKUYA;TSUTSUI, HIRONORI;TANAKA, MICHINORI;KAN, KEIZO;NAGAO, HITOSHI;WATANABE, KENJI;TAI, KUNINORI;NAKAGAWA, TAKASHI;TAKASU, HIDEKI;SAKAMOTO, MAKOTO;MIYAJIMA, KEISUKE;YAMADA, SATOSHI;KOJIMA, YUTAKA;YASUMURA, KOICHI;OHI, NAOTO;OKUNO, MITSUHIRO;SUGIYAMA, KAZUHISA;KIYONO, KUNIHIKO;SUZUKI, TAKASHI;AKAMATSU, SEIJI;KODAMA, TAKESHI;YANAGIHARA, YASUO;SUMIDA, TAKUMI 发明人 FUKUSHIMA, TAE;MATSUMURA, SHUJI;TAKEMURA, NORIAKI;SATOU, HIDEAKI;ITO, NOBUAKI;SHITSUTA, TAKUYA;TSUTSUI, HIRONORI;TANAKA, MICHINORI;KAN, KEIZO;NAGAO, HITOSHI;WATANABE, KENJI;TAI, KUNINORI;NAKAGAWA, TAKASHI;TAKASU, HIDEKI;SAKAMOTO, MAKOTO;MIYAJIMA, KEISUKE;YAMADA, SATOSHI;KOJIMA, YUTAKA;YASUMURA, KOICHI;OHI, NAOTO;OKUNO, MITSUHIRO;SUGIYAMA, KAZUHISA;KIYONO, KUNIHIKO;SUZUKI, TAKASHI;AKAMATSU, SEIJI;KODAMA, TAKESHI;YANAGIHARA, YASUO;SUMIDA, TAKUMI
分类号 C07D295/192;C07C233/67;C07D211/46;C07D211/58;C07D211/62;C07D211/70;C07D213/75;C07D239/42;C07D241/20;C07D295/185;C07D317/58;C07D401/12;C07D401/14;C07D405/12;C07D405/14 主分类号 C07D295/192
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