摘要 |
PROBLEM TO BE SOLVED: To provide a method for producing a highly pure dihalogenated biaryl derivative. SOLUTION: This method for producing the dihalogenated biaryl derivative of general formula (1) comprises recrystallizing a cross coupling reaction product of a 2-haloaryl metal reagent prepared by reacting a dihalogenated aryl compound with a Grignard reagent or the like, with a dihalogenated aryl derivative such as 2-bromo-3-iodonaphthalene in a mixture solvent of an aliphatic hydrocarbon solvent with a halogen-based solvent. COPYRIGHT: (C)2007,JPO&INPIT
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