METHOD OF PREDICTING SPOT FORMATION ON THE SKIN WITH THE USE OF SPOT SITE-ACCELERATING GENES AS INDICATION AND METHOD OF SCREENING INHIBITOR FOR SPOT FORMATION ON THE SKIN

摘要

It is intended to provide a skin examination method for predicting spot formation on the skin. This method is characterized by comprising judging the skin as having a high risk of spot formation in the case where the expression of MCP-2 gene, a polynucleotide hybridizable with mouse AK012157 gene, human FLJ21763 gene or rat S74257 gene under highly stringent conditions, or Mcp9, Mcp10, Isg15, Usp18, Oas 12, Gbp2, Gtpi, Ifi47, Igtp, Tgtp, Sprr2A, Krt2-6b, Cdk5rap2, Mef2C, Gsta4, Osf2, Tnc, Igfbp6, Ppicap, MCP-6 or Mm.74656 gene is accelerated in the epidermis compared with the expression thereof in normal epidermis.