COMPOSITION FOR EXTERNAL APPLICATION TO THE SKIN CONTAINING THE ACTIVE INGREDIENTS OF ITRACONAZOLE

摘要

A composition for external application containing itraconazole as active ingredient is provided to increase treating effects on fungal infection by improving skin permeability and deposition of itraconazole. The composition for external application contains itraconazole as active ingredient and noisome including itraconazole, wherein the composition is a cream type or gel type formulation; the composition further comprises ceramide; the pH of the composition is 6.5-8.5; and the viscosity of the composition is 400-1000 at shear rate of 76.8 sec^-1.