| 发明名称 |
HETEROARYL BENZAMIDE DERIVATIVES FOR USE AS GLK ACTIVATORS IN THE TREATMENT OF DIABETES |
| 摘要 |
<p>Compounds of formula (I), wherein R<SUP>1</SUP>, R<SUP>4</SUP>, HET-1 and HET-2 are as described in the specification, and their salts and pro-drugs, are activators of glucokinase (GLK) and are thereby useful in the treatment of, for example, type 2 diabetes. Processes for preparing compounds of formula (I) are also described.</p> |
| 申请公布号 |
WO2006125972(A1) |
申请公布日期 |
2006.11.30 |
| 申请号 |
WO2006GB01887 |
申请日期 |
2006.05.23 |
| 申请人 |
ASTRAZENECA AB;ASTRAZENECA UK LIMITED;MCKERRECHER, DARREN;PIKE, KURT, GORDON;WARING, MICHAEL, JAMES |
发明人 |
MCKERRECHER, DARREN;PIKE, KURT, GORDON;WARING, MICHAEL, JAMES |
| 分类号 |
C07D405/12;A61K31/4155;A61P3/04;A61P3/06;C07D403/12;C07D409/12;C07D411/12;C07D413/12;C07D413/14;C07D417/12;C07D419/12 |
主分类号 |
C07D405/12 |
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