The present invention is related to a highly purified pharmaceutical preparation comprising an acylated insulin where the acyl group is attached via a linker molecule to the e- amino group of the B29Lys residue of the parent insulin moiety. The insulin pharmaceutical formulation comprises less than about 3% weight/weight of an isomer of the acylated insulin.
申请公布号
WO2006125765(A2)
申请公布日期
2006.11.30
申请号
WO2006EP62495
申请日期
2006.05.22
申请人
NOVO NORDISK A/S;MARKUSSEN, JAN;HAVELUND, SVEND;JACOBSEN, JES KRISTIAN;HVASS, AAGE;JONASSEN, IB;JENSEN, GEORG WILHELM
发明人
MARKUSSEN, JAN;HAVELUND, SVEND;JACOBSEN, JES KRISTIAN;HVASS, AAGE;JONASSEN, IB;JENSEN, GEORG WILHELM
