| 发明名称 |
Antibodies that bind OPGL and compositions and methods for the treatment of bone diseases |
| 摘要 |
<p>An antibody that comprises a heavy and a light chain, wherein the heavy chain comprises SEQ ID NO:2 or a fragment that comprises at least one CDR and the light chain comprises SEQ ID NO:4 or a fragment that comprises at least one CDR and the antibody interacts with an osteoprotegerin ligand (OPGL). Also described are compositions and uses of the antibody for the treatment of bone disorders.</p> |
| 申请公布号 |
NZ530765(A) |
申请公布日期 |
2006.11.30 |
| 申请号 |
NZ20020530765 |
申请日期 |
2002.06.25 |
| 申请人 |
AMGEN FREMONT INC |
发明人 |
BOYLE, WILLIAM J;MARTIN, FRANCIS H;CORVALAN, JOSE R;DAVIS, GEOFFREY C |
| 分类号 |
C12N15/09;A61K31/519;A61K38/00;A61K39/395;A61K45/00;A61P19/08;A61P19/10;A61P29/00;A61P37/02;C07D475/10;C07K16/24;C07K16/28;C12P21/08;(IPC1-7):A61K39/395;C07K16/18;A61P19/00 |
主分类号 |
C12N15/09 |
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