| 发明名称 |
Inhibitors of akt activity |
| 摘要 |
The present invention is directed to compounds which contain a substituted pyridine moiety which inhibit the activity of Akt, a serine/threonine protein kinase. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for treating cancer comprising administration of the compounds of the invention.
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| 申请公布号 |
US2006270673(A1) |
申请公布日期 |
2006.11.30 |
| 申请号 |
US20050554187 |
申请日期 |
2005.10.21 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
DUGGAN MARK E.;LINDSLEY CRAIG W.;WU ZHICAI;ZHAO ZHIJIAN;HARTNETT JOHN C. |
| 分类号 |
A61K31/5377;A61K;A61K31/44;A61K31/4439;C07D213/02;C07D213/85;C07D401/04;C07D401/12;C07D401/14;C07D403/02;C07D413/02;C07D413/12;C07D417/02;C07D417/04;C07D417/12;C07D417/14 |
主分类号 |
A61K31/5377 |
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