发明名称 |
Pentopyranosyl nucleic acid conjugates |
摘要 |
The invention relates to compounds including at least one pentopyranosyl nucleic acid and a biomolecule conjugated through a covalent linkage to the at least one pentopyranosyl nucleic acid. The pentopyranosyl nucleic acid has at least two pentopyranosyl nucleotide subunits covalently linked between carbon 4 and carbon 2 of their respective pentopyranosyl rings. The pentopyranosyl nucleic acid does not non-covalently bond or hybridize to naturally occurring DNA or RNA. The invention also relates to compounds comprising a biotin molecule and a pentopyranosyl nucleic acid conjugated through a covalent linkage to the biotin molecule. Processes for preparing conjugates are also described.
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申请公布号 |
US2006270840(A1) |
申请公布日期 |
2006.11.30 |
申请号 |
US20060499543 |
申请日期 |
2006.08.03 |
申请人 |
MICULKA CHRISTIAN;WINDHAB NORBERT;BRANDSTETTER TILMANN;BURDINSKI GERHARD |
发明人 |
MICULKA CHRISTIAN;WINDHAB NORBERT;BRANDSTETTER TILMANN;BURDINSKI GERHARD |
分类号 |
C07H21/02;C12Q1/68;A61K49/00;C07H1/00;C07H19/04;C07H19/067;C07H21/00;C07H21/04;C07K16/00;G01N33/532 |
主分类号 |
C07H21/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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