Inhalation device for producing a drug aerosol with condensation of drug vapour
摘要
A device for delivering a drug by inhalation is disclosed. The device includes a body defining an interior flow-through chamber having upstream and downstream chamber openings, and a drug supply unit contained within the chamber for producing, upon actuation, a heated drug vapour in a condensation region of the chamber. Gas drawn through the chamber region at a selected gas-flow rate is effective to form drug condensation particles from the drug vapour having a selected MMAD (mass median aerodynamic diameter) between 0.02 and 0.1 micrometers or between 1 and 3.5 gm. A gas-flow control valve disposed upstream of the unit functions to limit gas-flow rate through the condensation region to the selected gas-flow rate. An actuation switch in the device activates the drug-supply unit, such that the drug-supply unit can be controlled to produce vapour when the gas-flow rate through the chamber is at the selected flow rate.
申请公布号
NZ540209(A)
申请公布日期
2006.11.30
申请号
NZ20030540209
申请日期
2003.10.16
申请人
ALEXZA PHARMACEUTICALS, INC
发明人
CROSS, STEPHEN;HODGES, CRAIG C;HALE, RON L;LLOYD, PETER M;MEYERS, DANIEL J;QUINTANA, REYNALDO J;RABINOWITZ, JOSHUA D;TOM, CURTIS;WENSLEY, MARTIN J