发明名称 A PROCESS FOR THE CRYSTALLIZATION OF ROSIGLITAZONE AND ITS DERIVATIVES FROM MIXED SOLVENTS
摘要 <p>Crystallization of rosiglitazone of formula (I), its penultimate of formula (II), or salts with acids of formula (III), wherein HX stands for a mineral or carboxylic acid, is carried out from mixed organic solvents, consisting of mixtures of carboxylic acids, particularly formic acid, acetic acid or propionic acid, with aliphatic alcohols, particularly methanol, ethanol, 1-propanol, 2- propanol, butanols or amyl alcohols.</p>
申请公布号 WO2006125402(A1) 申请公布日期 2006.11.30
申请号 WO2006CZ00034 申请日期 2006.05.19
申请人 ZENTIVA, A.S.;HALAMA, ALES;RICHTER, JLNDRICH 发明人 HALAMA, ALES;RICHTER, JLNDRICH
分类号 C07D417/12 主分类号 C07D417/12
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