发明名称 |
PROCESS FOR THE PREPARATION OF N-AMINO SUBSTITUTED HETEROCYCLIC COMPOUNDS |
摘要 |
An improved process for the preparation of N-amino nitrogen heterocyclic compounds is disclosed and claimed. In an ambodiment of this invention, a compound of the formula (VI) is prepared starting from the corresponding indole derivative by way of N- amination and subsequently forming an hydrazone by the reaction with a keto compound in a single step. Further reduction of the hydrazone and subsequent coupling with a pyridine compound affords the compound of formula VI or a suitable salt thereof.
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申请公布号 |
KR20060120028(A) |
申请公布日期 |
2006.11.24 |
申请号 |
KR20067006835 |
申请日期 |
2006.04.07 |
申请人 |
AVENTIS PHARMACEUTICALS, INC. |
发明人 |
WEIBERTH FRANZ;LEE GEORGE E.;HANNA REDA G.;DUBBERKE SILKE;UTZ ROLAND;MUELLER LEHAR JURGEN |
分类号 |
C07D209/30;A61K31/405;C07D209/08;C07D209/86;C07D401/04;C07D401/12 |
主分类号 |
C07D209/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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