| 摘要 |
PROBLEM TO BE SOLVED: To provide a 3-aminoisoxazole (hydrogen) sulfate salt with very low hazard compared to 3-aminoisoxazole and 3-aminoisoxazole hydrochloride, and to provide a method for producing the 3-aminoisoxazole (hydrogen) sulfate salt. SOLUTION: The 3-aminoisoxazole (hydrogen) sulfate salt is represented by general formula(1)( wherein, n is 1 or 2 ). The method for producing the 3-aminoisoxazole (hydrogen) sulfate salt comprises carrying out a reaction between a 3-alkoxyacrylonitrile of general formula(2)( wherein, R is an alkyl ) and hydroxylamine( or its acid salt ) in the presence of a base to form 3-aminoisoxazole followed by reacting sulfuric acid with the 3-aminoisoxazole. COPYRIGHT: (C)2007,JPO&INPIT
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