There is provided a method of conjugating a polymer containing a free aldehyde group with a flavonoid in the presence of an acid catalyst, such that the polymer is conjugated to the C6 or C8 position of the flavonoid A ring. The resulting conjugates may be used to form delivery vehicles to deliver high doses of flavonoids, and may also be used as delivery vehicles to deliver an additional bioactive agent.
申请公布号
WO2006124000(A1)
申请公布日期
2006.11.23
申请号
WO2006SG00045
申请日期
2006.03.07
申请人
AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH;ZHUO, LANG;CHUNG, JOO EUN;KURISAWA, MOTOICHI;YANG, YI YAN
发明人
ZHUO, LANG;CHUNG, JOO EUN;KURISAWA, MOTOICHI;YANG, YI YAN