| 摘要 |
An implantable flow regulator ( 22 ) for regulating flow of a drug along a drug delivery pathway ( 14 ) from a drug source to a treatment site within a subject includes a movable diversion member ( 24 ) and an actuator. The movable diversion member ( 24 ) is operably coupled to a delivery pathway ( 14 ). The actuator is actuatable to move the diversion member ( 24 ) between at least a first mode position where the diversion member ( 24 ) restricts flow through the delivery pathway ( 14 ) (i.e., delivery pathway is "closed"), and a second mode position where the diversion member ( 24 ) is position to allow flow through the delivery pathway ( 14 ) (i.e., delivery pathway is "open"). Supplying power to actuate the actuator moves the diversion member ( 24 ) from its normally biased first mode or "closed" position, which is also a failsafe position, toward its second mode or "open" position. In the "open" position, drug is supplied to target sites, typically from a drug supply reserve within the regulator.
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