发明名称 |
Process for the preparation of hypoallergenic mosaic antigens |
摘要 |
A process for the preparation of an hypoallergenic mosaic antigen derived from an allergen is disclosed whereby a) in a first step the allergen is split into at least two parts and the IgE reactivity of each part is determined and b) in a second step those parts of the allergen which have no detectable IgE reaction are combined to a mosaic antigen which comprises the amino acids of the allergen but the order of the amino acids of the mosaic antigen is different from that of the naturally occurring allergen.
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申请公布号 |
US2006263391(A1) |
申请公布日期 |
2006.11.23 |
申请号 |
US20050542735 |
申请日期 |
2005.07.21 |
申请人 |
MOTHES NADINE;STUMVOLL SABINE;FOCKE MARGIT;LINHART BIRGIT;KRAUTH MARIA-THERESA;VALENT PETER;KRAFT DIETRICH;VALENTA RUDOLF |
发明人 |
MOTHES NADINE;STUMVOLL SABINE;FOCKE MARGIT;LINHART BIRGIT;KRAUTH MARIA-THERESA;VALENT PETER;KRAFT DIETRICH;VALENTA RUDOLF |
分类号 |
A61K39/35;A61K38/00;C07K14/415;C12N5/04;C12N15/82 |
主分类号 |
A61K39/35 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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