DIBENZODIAZEPINONE ANALOGUES, PROCESSES FOR THEIR PRODUCTIONAND THEIR USE AS PHARMACEUTICALS

摘要

This invention relates to novel dibenzodiazepinone analogs, and to pharmaceutically acceptable salts, solvates and prodrugs, to pharmaceutical compositions comprising them, and to methods for obtaining such compounds. O ne method of obtaining the dibenzodiazepinone analogs is by post-biosynthesis chemical modifications of the farnesyl dibenzodiazepinone ECO-4601. The dibenzodiazepinone analogs are useful as pharmaceuticals, in particular as antineoplastic agent s.