发明名称 DEUTERIUM DEPLETED WATER (DDW) USING AS ADJUVANT IN CANCER THERAPY FOR CYTOSTATICS TOXICITY REDUCTION
摘要 The hereby invention addresses to a new application of Deuterium Depleted Water (DDW), namely, its administering, on a concentration of 60 ppm, as daily diet, to adult healthy outbred Wistar rats produces a distinguished lowering of toxic effects produced by cytostatics (Cyclophosphamide, 5-Flourouracil, Farmarubicine and Vinblastine) when they used in these animals mono-chemotherapy. Also, the 60 ppm DDW administering under similar conditions generates a significant cytostatics toxicity (Cyclophosphamide, 5-Flourouracil, Farmarubicine and Vinblastine) used in polychimiotherapy on pet dogs having different types of cancer. These relevant findings confirm the idea of 60 ppm DDW as a new and efficient adjuvant in cancer chemotherapy on pets and humans.
申请公布号 WO2006019327(B1) 申请公布日期 2006.11.09
申请号 WO2005RO00008 申请日期 2005.07.26
申请人 REGIA AUTONOMA PENTRU ACTIVITATI NUCLEARE DROBETATURNU SEVERIN;MANOLESCU, NICOLAE;VALECA, SERBAN CONSTANTIN;ANGHEL, RODICA;BALANESCU, ION;TRAICU, RODIN;MARCULESCU, DUMITRU;STEFANESCU, IOAN;PANAIT, MARIETA;BALINT, EMILIA;ENCUT, IOAN;MILITARU, MANUELLA;POP, ANETA;CINCA, SABIN;COMISEL, VIRGILIU;FUGARU, VIOREL;MATEESCU, CORNELIU;GRUIA, IULIANA;MORARU, VICTORIA;NISTOROIU, MONICA;BEGU, DANIELA;DUMITRESCU, IOLANDA;GHITA, MARIA 发明人 MANOLESCU, NICOLAE;VALECA, SERBAN CONSTANTIN;ANGHEL, RODICA;BALANESCU, ION;TRAICU, RODIN;MARCULESCU, DUMITRU;STEFANESCU, IOAN;PANAIT, MARIETA;BALINT, EMILIA;ENCUT, IOAN;MILITARU, MANUELLA;POP, ANETA;CINCA, SABIN;COMISEL, VIRGILIU;FUGARU, VIOREL;MATEESCU, CORNELIU;GRUIA, IULIANA;MORARU, VICTORIA;NISTOROIU, MONICA;BEGU, DANIELA;DUMITRESCU, IOLANDA;GHITA, MARIA
分类号 A61K47/02;A61K31/35;A61K31/475;A61K31/675;A61K33/00;A61P35/00 主分类号 A61K47/02
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