发明名称 |
DIASTEREOISOMERS OF 4-HYDROXYISOLEUCINE AND USES THEREOF |
摘要 |
The invention relates to configurational isomers 4-hydroxyisoleucine, and to lactones, pharmaceutically acceptable salts, and prodrugs thereof, to processes for their preparation, and to pharmaceutical compositions comprising the same. The isomers of the invention exhibit insulinotropic activity and thus may be useful for the prevention and treatment of disorders of carbohydrate or lipid metabolism, including diabetes mellitus (type 1 and type 2 diabetes), pre-diabetes, and Metabolic Syndrome. |
申请公布号 |
WO2006117696(A2) |
申请公布日期 |
2006.11.09 |
申请号 |
WO2006IB01758 |
申请日期 |
2006.02.17 |
申请人 |
INNODIA INC.;CONSEIL NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.);UNIVERSITE LOUIS PASTEUR STRASBOURG I;COQUELET, CLAUDE;MIOSKOWSKI, CHARLES;WAGNER, ALAIN |
发明人 |
COQUELET, CLAUDE;MIOSKOWSKI, CHARLES;WAGNER, ALAIN |
分类号 |
C07C229/22;A61K31/198;A61P3/10;C07D307/32 |
主分类号 |
C07C229/22 |
代理机构 |
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代理人 |
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