NOVEL PYRIDINE DERIVATIVE AND PYRIMIDINE DERIVATIVE (2)

摘要

A compound represented by the following formula, a salt thereof or a hydrate of the foregoing has an excellent hepatocyte growth factor receptor (HGFR) inhibitory activity, and exhibits anti-tumor activity, angiogenesis inhibitory activity and cancer metastasis inhibitory activity.
[R 1 represents C 1-6 alkyl or the like; R 2 and R 3 represent hydrogen;
R 4 , R 5 , R 6 , and R 7 may be the same or different and each represents hydrogen, halogen, C 1-6 alkyl or the like; R 8 represents hydrogen or the like; R 9b represents a 3- to 10-memberd non-aromatic heterocyclic group or the like; V 1 represents oxygen or the like; V 2 represents oxygen or sulfur; W represents -CH 2 - or the like; X represents -CH=, nitrogen or the like; and Y represents oxygen or the like.]