| 发明名称 |
1-THIA-3-AZA-DIBENZOAZULENES AS INHIBITORS OF TUMOUR NECROSIS FACTOR PRODUCTION AND INTERMEDIATES FOR THE PREPARATION THEREOF |
| 摘要 |
The present invention relates to derivatives of 1-thia-3-aza-dibenzoazulene class, to their pharmacologically acceptable salts and solvates, to processes and intermediates for the preparation thereof as well as to their antiinflammatory effects, especially to the inhibition of tumour necrosis factor-a (TNF-(x) production and the inhibition of interleukin-1 (IL-1) production as well as to their analgetic action.
|
| 申请公布号 |
RS100004(A) |
申请公布日期 |
2006.10.27 |
| 申请号 |
YU2004P001000 |
申请日期 |
2003.05.20 |
| 申请人 |
PLIVA ISTRAZIVACKI INSTITUT D.O.O. |
发明人 |
MERCEP MLADEN;MESIC MILAN;MODRIC MARINA;PESIC DIJANA;KIDEMET DAVOR |
| 分类号 |
C07D417/04;A61K31/428;A61K31/43;A61K31/55;A61P1/04;A61P3/10;A61P9/02;A61P11/00;A61P11/06;A61P13/12;A61P17/00;A61P17/06;A61P25/28;A61P27/02;A61P29/00;A61P29/02;A61P35/00;A61P43/00;C07D513/02;C07D513/04;(IPC1-7):C07D513/04 |
主分类号 |
C07D417/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
