The invention provides HGF/Met modulators comprising HGF having mutations in regions that affect HGF function, and antagonists that target said regions. The invention further provides methods of identifying, making and using thes e modulators.
申请公布号
CA2605037(A1)
申请公布日期
2006.10.26
申请号
CA20062605037
申请日期
2006.04.17
申请人
GENENTECH, INC.
发明人
KIRCHHOFER, DANIEL K.;LAZARUS, ROBERT A.;WIESMANN, CHRISTIAN