发明名称 |
CATHETER ASSEMBLY WITH BACTERICIDAL EFFECT |
摘要 |
<p>A use in a medical device of at least one salt of organic acid(s), and preferably a benzoate or a sorbate, as an antimicrobial agent is disclosed, and in particular for the manufacturing of an antimicrobial coating for a medical device for the prevention of bacterial infection. This is very useful in medical devices having a hydrophilic coating, such hydrophilic urinary catheters. It is further preferred that the pH of the hydrophilic coating is controlled to be in the range 4.0 - 8.0, and preferably in the range 5.0 - 6.0. It is also preferred that the pH of the hydrophilic coating is controlled to be below 7.0. The pH of the hydrophilic coating could be controlled by means of a pH buffer, and preferably a citrate or phosphate buffer. Specifically, the provision of the salt of organic acid in combination with a pH buffer has proven surprisingly efficient for inhibition of bacterial growth, and for prevention of bacterial infections.</p> |
申请公布号 |
WO2006112782(A1) |
申请公布日期 |
2006.10.26 |
申请号 |
WO2006SE00466 |
申请日期 |
2006.04.21 |
申请人 |
ASTRA TECH AB;UTAS, JAN;SCHMID, ANDREA;NORDHOLM, AGNETA;NYMAN, MARTIN |
发明人 |
UTAS, JAN;SCHMID, ANDREA;NORDHOLM, AGNETA;NYMAN, MARTIN |
分类号 |
A61L29/08;A61L27/28;A61L27/54;A61L29/16 |
主分类号 |
A61L29/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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