发明名称 |
Orally disintegrating pharmaceutical tablet formulations of olanzapine |
摘要 |
This invention provides orally disintegrating pharmaceutical tablet formulations comprising per tablet the following ingredients in the following percentages by weight: olanzapine as an active ingredient in an amount from about 2.5% to about 10%; mannitol in an amount from about 75% to about 95%; a disintegrating agent in an amount from about 1.0% to about 10%; and one or more excipient in a total amount of about 0.1% to about 10%. This invention also provides a method of treating a patient in need of treatment with olanzapine which comprises administering to the patient a therapeutically effective dose of the above pharmaceutical tablet formulations. Finally, this invention provides a method of producing the above pharmaceutical tablet formulation which comprises combining the ingredients in the appropriate relative percentages by weight.
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申请公布号 |
US2006240101(A1) |
申请公布日期 |
2006.10.26 |
申请号 |
US20060402416 |
申请日期 |
2006.04.11 |
申请人 |
CHUNGI SHUBHA;BARNES CLAUDE R;LONESKY STEVEN M |
发明人 |
CHUNGI SHUBHA;BARNES CLAUDE R.;LONESKY STEVEN M. |
分类号 |
A61K31/551;A61K9/20 |
主分类号 |
A61K31/551 |
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地址 |
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