METHOD OF EXAMINING METASTATIC PROPERTY AND INFILTRATION ABILITY OF CANCER

摘要

[PROBLEMS] To provide a method for examining cancer with poor prognosis. [MEANS FOR SOLVING PROBLEMS] It is found out that the expression of a G protein-coupled receptor GPR48 gene (AF257182) is significantly accelerated in cancer with poor prognosis. As the results of the subsequent studies aiming at clarifying the relationship between GPR48 and cancer metastasis, it is found out that GPR48 has a function of accelerating the infiltration ability of cancer cells and the obtained results are applied to the diagnosis of cancer with poor prognosis. Namely, a method of examining the metastatic property of caner and a method of examining the infiltration ability of cancer comprising detecting the expression of the G protein-coupled receptor GPR48 in a cell or tissue to be examined.