ANTIBODY REACTIVE SPECIFICALLY TO AGE DERIVED FROM 3,4-DGE

摘要

Disclosed is an antibody against an AGE derived from a carbonyl compound which is highly reactive with a protein or peptide. Also disclosed is a method for detecting the AGF. 3,4-dideoxyglucosone-3-ene (3,4-DGE) is reacted with a protein to produce a reaction product AGE. A host animal is immunized with the AGE, the serum is collected from the host animal, and an antibody against the AGE (anti-AGE antibody) is isolated from the serum. The presence or content of a AGE in a sample can be determined by allowing the isolated anti-AGE antibody to react with the sample and detecting the antigen-antibody reaction between the AGE and the anti-AGE antibody in the sample.