发明名称 |
ASSAYS FOR DETECTING THE TAT PROTEIN IN HIV-1 INFECTION |
摘要 |
A method for detecting or measuring HIV-I Transactivating (Tat) protein in a biological sample comprising contacting the biological sample with an amount of a basic protein effective to reduce interference with binding between anti-HIV-1 Tat Epitope 2 ligand and Tat that is caused by acidic components within the sample or reagents. A more accurate detection and measurement of the amount of HIV-I Tat in the sample is obtained by binding between the anti-Epitope 2 antibody and the Tat in the sample when the interference is neutralized. A diagnostic kit for use in practicing the method contains these components. Preferred basic proteins are protamine sulfate, poly-Arg and poly-Lys .
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申请公布号 |
WO2006088739(A8) |
申请公布日期 |
2006.10.19 |
申请号 |
WO2006US04781 |
申请日期 |
2006.02.13 |
申请人 |
THYMON, L.L.C.;GOLDSTEIN, GIDEON |
发明人 |
GOLDSTEIN, GIDEON |
分类号 |
G01N33/569;G01N33/53 |
主分类号 |
G01N33/569 |
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