发明名称 Hybrid phthalocyanine derivatives and their uses
摘要 Water soluble hybrid phthalocyanine derivatives useful in competitive and noncompetitive assays immunoassays, nucleic acid and assays are disclosed and claimed having (1) at least one donor subunit with a desired excitation peak, and (2) at least one acceptor subunit with a desired emission peak, wherein said derivative(s) is/are capable of intramolecular energy transfer from said donor subunit to said acceptor subunit. Such derivatives also may contain an electron transfer subunit. Axial ligands may be covalently bound to the metals contained in the water soluble hybrid phthalocyanine derivatives. Ligands, ligand analogues, polypeptides, proteins and nucleic acids can be linked to the axial ligands of the dyes to form dye conjugates useful in immunoassays and nucleic acid assays.
申请公布号 US2006228748(A1) 申请公布日期 2006.10.12
申请号 US20060448613 申请日期 2006.06.06
申请人 BIOSITE INCORPORATED 发明人 BUECHLER KENNETH F.;NOAR JOSEPH B.;TADESSE LEMA
分类号 C12Q1/68;C07F7/02;G01N33/551 主分类号 C12Q1/68
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