| 发明名称 |
BENZYLOXYPROPYLAMINE DERIVATIVE |
| 摘要 |
<p>Disclosed is a novel benzyloxypropylamine derivative having an excellent tachykinin receptor antagonistic effect. This compound shows a good transfer into the blood and a long blood half-life in the blood kinetic test using a guinea pig orally administered with the compound and is stable in an animal plasma. The compound also shows a high transfer to the central nervous system when it is orally administered to a guinea pig at a certain dose. Accordingly, the benzyloxypropylamine derivative is quite useful as a novel anti-tachykinin agent.</p> |
| 申请公布号 |
WO2006106727(A1) |
申请公布日期 |
2006.10.12 |
| 申请号 |
WO2006JP306451 |
申请日期 |
2006.03.29 |
| 申请人 |
NIPPON ZOKI PHARMACEUTICAL CO., LTD.;HIGASHIURA, KUNIHIKO;OGINO, TAKASHI;FURUKAWA, KAZUHITO |
发明人 |
HIGASHIURA, KUNIHIKO;OGINO, TAKASHI;FURUKAWA, KAZUHITO |
| 分类号 |
C07C233/18;A61K31/165;A61K31/166;A61K31/192;A61K31/22;A61K31/27;A61K31/40;A61K31/4402;A61K31/4406;A61K31/4409;A61K31/445;A61K31/4465;A61K31/4468;A61K31/4545;A61K31/455;A61K31/47;A61K31/4965;A61P1/08;A61P1/12;A61P9/10;A61P17/00;A61P21/02;A61P25/04;A61P25/08;A61P25/22;A61P25/24;A61P29/00;A61P37/06;A61P37/08;A61P43/00;C07C233/70;C07C233/73;C07C235/48;C07C237/08;C07C237/24;C07C237/32;C07C271/22;C07C271/24;C07C271/48;C07D211/58;C07D211/62;C07D213/56;C07D213/81;C07D213/89;C07D215/50;C07D241/24;C07D295/14 |
主分类号 |
C07C233/18 |
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