发明名称 Improved formulations of fenofibrate
摘要 <p>The invention provides at least a composition for the treatment of elevated levels of triglycerides, comprising a therapeutically effective amount of fenofibrate or another fibrate drug intimately associated with menthol or a surfactant mixture, wherein the menthol can be menthol or menthol surfactant mixture, and wherein the surfactant mixture can be a mixture of a polyethylene glycol and a poloxamer such as PGE 1000 and poloxamer 407. The invention also provides a method for the treatment of elevated levels of triglycerides in a subject, comprising administering to the subject a composition comprising a therapeutically effective amount of fenofibrate or another fibrate drug and menthol or a surfactant mixture, wherein the fenofibrate or the other fibrate drug is in intimate association with the menthol or surfactant mixture, wherein the menthol can be menthol or menthol surfactant mixture, and wherein the surfactant mixture can be a mixture of a polyethylene glycol and a poloxamer such as PGE 1000 and poloxamer 407.</p>
申请公布号 EP1707196(A1) 申请公布日期 2006.10.04
申请号 EP20050258102 申请日期 2005.12.29
申请人 TEVA PHARMACEUTICAL INDUSTRIES LTD. 发明人 FLASHNER-BARAK, MOSHE;LERNER, E. ITZHAK;ROSENBERGER, VERED;MOLDAVSKI, NAOMI
分类号 A61K31/216;A61K47/10 主分类号 A61K31/216
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