发明名称 |
Method of testing for atopic dermatitis by measuring expression of the NOR-1 gene |
摘要 |
Genes whose expression differ between that in eosinophils collected from atopic dermatitis patients of the exabartation stage and those of the remission stage were searched via a differential display method. As a result, NOR-1 (MINOR) gene was successfully identified whose expression significantly increased in eosinophils of patients in the remission stage, a stage associated with a decrease of eosinophils. The present inventors discovered that the gene can be successfully employed in testing for allergic diseases and screening for candidate compounds for therapeutic agents.
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申请公布号 |
US7115373(B2) |
申请公布日期 |
2006.10.03 |
申请号 |
US20030608863 |
申请日期 |
2003.06.27 |
申请人 |
JAPAN AS REPRESENTED BY GENERAL DIRECTOR OF AGENCY OF NATIONAL CENTER FOR CHILD HEALTH & DEVELOPMENT |
发明人 |
HASHIDA RYOICHI;KAGAYA SHINJI;YAYOI YOSHIHIRO;SUGITA YUJI;SAITO HIROHISA |
分类号 |
C12Q1/68;A01K67/027;A61P37/08;C07H21/04;C07K14/705;C12N5/08;C12N15/85;G01N33/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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地址 |
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