HETEROARYL DERIVATIVES AS SUPERIOR LIGANDS FOR NOCICEPTIN RECEPTOR ORL-1

摘要

NOVEL COMPOUNDS OF THE FORMULA, WHEREIN R IS OPTIONALLY SUBSTITUTED HETEROARYL OR ; R1 IS H OR C1-C6 ALKYL; AND R2 AND R3 ARE -CH3, -OCH3 OR HALO; OR A PHARMACEUTICALY ACCEPTABLE SALT OR SOLVATE THEREOF, PHARMACEUTICAL COMPOSITIONS THEREFORE, AND THE USE OF SAID COMPOUNDS IN THE TREATMENT OF PAIN , ANXIETY, COUGH, ASTHMA, DEPRESSION AND ALCOHOL ABUSE ARE DISCLOSED.