发明名称 A PROCESS FOR THE SIMULTANEOUS PRODUCTION OF ARTEMISININ ANDESSENTIAL OIL FROM THE PLANT ARTEMISIA ANNUA
摘要 This invention relates to a novel process for the dual production of essenti al oil and artemisinin from the plant Artemisia annua, said process comprising extracting the plant with hexane, partitioning the hexane extract between hexane and acetonitrile, hydrodistillation of hexane residue and Marc to yie ld essential oil, further fractionation of acetonitrile solvent between hexane- benzene mixture to remove artemisinic acid, chromatographing of the acetonitrile phase to produce substancially pure artemisinin, the artemisini c acid is reduced to obtain dihydro artemisinic acid which is then oxidised in a single step to foam artemisinin.
申请公布号 CA2218444(C) 申请公布日期 2006.09.26
申请号 CA19972218444 申请日期 1997.10.16
申请人 COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH 发明人 JAIN, DHARAM CHAND;SIDDIQUE, MOHAMMED SHAFIQUE;KAHOL, ATUL PRAKASH;SHARMA, RAM PRAKASH;KUMAR, SUSHIL;BHAKUNI, RAJENDRA SINGH;TANDON, SUDEEP;BHATTACHARYA, ASISH KUMAR
分类号 C07D493/18;A61K36/00;A61K36/282;C07C51/48;C07C57/26;C07D493/20;C11B5/00;C11B9/02;C11B13/00 主分类号 C07D493/18
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