The invention is directed to methods for preparing artificial heart valves by preconditioning a matrix seeded with endothelial cells and smooth muscle cells differentiated from isolated progenitor cells. These cell seeded matrices are exposed to fluid conditions that mimic blood flow through the heart to produce tissue engineered heart valves that are analogous to native heart valves.
申请公布号
WO2006099334(A2)
申请公布日期
2006.09.21
申请号
WO2006US08964
申请日期
2006.03.10
申请人
WAKE FOREST UNIVERSITY HEALTH SCIENCES;ATALA, ANTHONY;YOO, JAMES