发明名称 PROCESS AND METHODS FOR THE PREPARATION OF OPTICALLY ACTIVE CIS-2-HYDROXYMETHYL-4-(CYTOSIN-1´-YL)-1,3-OXATHIOLANE OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF
摘要 <p>There is provided a method for resolving a compound of formula (III), in the cis configuration: There is also provided a process for producing optically active compound of formula (I) or (II): wherein: R&lt;SUB&gt;1&lt;/SUB&gt;, R&lt;SUB&gt;2&lt;/SUB&gt;, R&lt;SUB&gt;3&lt;/SUB&gt; are as defined herein, the method and process involving the production, recovery and conversion of diastereomeric salts.</p>
申请公布号 WO2006096954(A1) 申请公布日期 2006.09.21
申请号 WO2005CA00384 申请日期 2005.03.14
申请人 SHIRE BIOCHEM INC.;CIMPOIA, ALEX 发明人 CIMPOIA, ALEX;SIMION, DAN
分类号 C07D411/04 主分类号 C07D411/04
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