CHROMEN-4-ONE INHIBITORS OF ANTI-APOPTOTIC BCL-2 FAMILY MEMBERS AND THE USES THEREOF
摘要
<p>The invention relates to small molecules which function as inhibitors of anti-apoptotic Bcl-2 family member proteins (e.g., Bcl-2 and Bcl-xL). The invention also relates to the use of these compounds for inducing apoptotic cell death and sensitizing cells to the induction of apoptotic cell death.</p>
申请公布号
WO2006099193(A2)
申请公布日期
2006.09.21
申请号
WO2006US08690
申请日期
2006.03.13
申请人
THE REGENTS OF THE UNIVERSITY OF MICHIGAN;WANG, SHAOMENG;DING, KE;TANG, GUOZHI;WANG, RENXIAO;YANG, CHAO-YIE;NIKOLOVSKA-COLESKA, ZANETA