SOFT CAPSULE CONTAINING BUTYLPHTHALIDE AND ITS PREPARATION PROCEDURE
摘要
<p>The present invention discloses a novel soft capsule of butylphthalide and a process for preparing the same. The soft capsule of butylphthalide is composed of a capsule wall material and a drug-containing oil, wherein the drug-containing oil is essentially composed of butylphthalide and a vegetable oil as the diluent in a weight ratio of about 1:0~10. The capsule wall material is composed of a capsule wall matrix, a plasticizer and water in a weight ratio of 1:0.2~0.4:0.8~1.3. The soft capsule of butylphthalide described in the present invention can mask the strong and special flavour of butylphthalide, and overcome the difficulties associated with formulating oily active ingredient into other oral formulation. The disintegration time of the soft capsule satisfies the requirement of Pharmacopoeia of P.R. China.</p>
申请公布号
EP1702612(A1)
申请公布日期
2006.09.20
申请号
EP20040802425
申请日期
2004.12.03
申请人
SHIJIAZHUANG PHARMA. GROUP ZHONGQI PHARMACEUTICALTECHNOLOGY (SHIJIAZHUANG) CO., LTD.;SHIJIAZHUANG PHARMA. GROUP NBP PHARMACEUTICAL CO., LTD.