发明名称 |
Methods of identifying modulators of the FGF receptor |
摘要 |
The present invention provides fragments of SNT and FGFR which can form a binding complex that is amenable to structural determinations by NMR spectroscopy. The three-dimensional structural data is also included as part of the invention. In addition, the present invention provides methodology for related structure based rational drug design using the three-dimensional data. Nucleotide and amino acid sequences of the fragments are also provided.
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申请公布号 |
US7108984(B2) |
申请公布日期 |
2006.09.19 |
申请号 |
US20010757415 |
申请日期 |
2001.01.09 |
申请人 |
MOUNT SINAI SCHOOL OF MEDICINE |
发明人 |
ZHOU MING-MING;GOLDFARB MITCHELL |
分类号 |
G01N33/53;C07K14/475;C07K14/71;G06F19/00 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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