| 摘要 |
A method is provided for the induction of aberrant RNA interference (abRNAi) by introducing 'aberrant' RNAs into the cell wherein a long-stranded antisense or sense RNA is simultaneously introduced with a short 4-12 mer homologous or complementary or random RNA wherein the long-short RNAs induce sequence specific inhibition of the homologous gene within a cell. The invention disclosed herein can be used to suppress gene expression in vitro, ex vivo or in vivo.
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