发明名称 |
TYROSINE KINASE INHIBITOR COMPOSITIONS AND METHODS FOR MANUFACTURING AND USING THEM IN THE TREATMENT OF DISEASE |
摘要 |
A new ErbB-based ligand binding molecule is disclosed along with its method of preparation and use. The binding molecule is a protein expressed from a recombinant DNA molecule. The protein contains an ErbB extracellular domain that binds to activating ligands. These binding elements act as traps to bin d and sequester circulating ligands, thus making them unavailable for binding to cellular ErbB receptors.
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申请公布号 |
CA2600375(A1) |
申请公布日期 |
2006.09.14 |
申请号 |
CA20062600375 |
申请日期 |
2006.03.06 |
申请人 |
TARGETED MOLECULAR DIAGNOSTICS, LLC |
发明人 |
HILL, JASON E.;BACUS, SARAH S. |
分类号 |
C07K16/28 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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