COMPUTATIONAL SELECTION OF PROBES FOR LOCALIZING CHROMOSOME BREAKPOINTS

摘要

The present invention provides a novel method for selecting genomic hybridization probes. The method generally includes the step of selecting a genomic interval of interest, identifying at least one potential hybridization probe that has known coordinates within the interval of interest, applying a numerical method to sample the identified probe(s) based on its genome coordinates, and selecting a probe based on the result of the numerical method.