发明名称 |
TRANSPLANTABLE BIOMATERIAL AND METHOD OF PREPARING THE SAME |
摘要 |
<p>Decellularized tissues prepared by conventional technology are occasionally to be improved with respect to the strength, etc. thereof according to situations. The reason is that cells are removed from tissues by the decellularization, occasionally resulting in poor strength of the tissues. It is intended to provide a method of increasing the tissue strength for the decellularized tissues. There is provided a method comprising treating the decellularized tissues with a biocompatible polymer. Unexpectedly strong reinforcing effect for the decellularized tissues by a biocompatible polymer, preferably one polymerized through radical reaction using gamma rays, etc. has been found. Decellularization can be performed by the use of arbitrary technique, for example, using a surfactant such as SDS, or using an amphiphilic molecule such as PEG.</p> |
申请公布号 |
EP1698358(A1) |
申请公布日期 |
2006.09.06 |
申请号 |
EP20040807796 |
申请日期 |
2004.12.24 |
申请人 |
CARDIO INCORPORATED;OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION |
发明人 |
MATSUDA, HIKARU;SAWA, YOSHIKI;TAKETANI, SATOSHI;MIYAGAWA, SHIGERU;IWAI, SHIGEMITSU;OTA, TAKEYOSHI;HARA, MASAYUKI;FURUTA, MASAKAZU |
分类号 |
A61L27/40;A61F2/06;A61F2/24;A61F2/28;A61L27/38;C12N5/06;C12N5/08 |
主分类号 |
A61L27/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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