摘要 |
<p>The invention relates to compounds having formulae (I) and (II) wherein R1 and R2 are independently hydrogen or C1-C6 alkyl; X is N or CH; and R3 is phenyl, naphtyl, heteroaryl, substituted phenyl, substituted naphtyl, or substituted heteroaryl, wherein each substituent is independently selected from halogen, C1-C6 alkoxy, C1-C6 alkyl, -CN, -CF3 or sulphonamido and pharmaceutically acceptable salts, esters, amides prodrugs thereof, that are antagonists of dopamine D4 receptor.</p> |