发明名称 2,5-Disubstituted 3-mercaptopentanoic acid
摘要 The present invention concerns compounds of formula (I), and pharmaceutically acceptable salts or solvates thereof, or solvates of such salts, which compounds inhibit carboxypeptidase U and thus can be used in the prevention and treatment of diseases where inhibition of carboxypeptidase U is beneficial. In further aspects, the invention relates to compounds of the invention for use in therapy; to processes for preparation of such new compounds; to pharmaceutical compositions containing at least one compound of the invention, or a pharmaceutically acceptable salt or solvate thereof, as active ingredient; and to the use of the active compounds in the manufacture of medicaments for the medical use indicated above.
申请公布号 ZA200409955(B) 申请公布日期 2006.08.30
申请号 ZA20040009955 申请日期 2004.12.08
申请人 ASTRAZENECA AB 发明人 MAGNUS POLLA
分类号 C07D277/20;A61K;A61K31/426;A61K31/427;A61K31/435;A61K31/439;A61K31/44;A61K31/506;A61P;A61P1/16;A61P7/02;A61P9/10;A61P11/00;A61P17/00;A61P29/00;A61P35/00;A61P43/00;C07D;C07D211/34;C07D213/73;C07D213/74;C07D213/76;C07D221/22;C07D277/40;C07D277/42;C07D401/06;C07D401/12;C07D405/06;C07D405/12;C07D409/06;C07D409/12 主分类号 C07D277/20
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