METHODS FOR DETECTING PROGRESSION OF LOW GRADE CERVICAL DYSPLASIA AND FOR DETECTING ADENOCARCINOMAS

摘要

A kit for identifying a patient at risk of developing invasive cervical carcinoma comprising:
(a) a probe for detecting a genomic amplification of chromosome 3q; and
(b) instructions for using the probe to identify a patient at risk of developing invasive cervical carcinoma in accordance a method comprising:
detecting any genomic amplification of chromosome 3q in a sample obtained from a patient having
i) low grade cervical dysplasia; or
ii) no dysplasia
thereby identifying a patient at risk of developing invasive cervical carcinoma if a genomic amplification of chromosome 3q is detected.