发明名称 |
Recombinant cell clones having increased stability and methods of making and using the same |
摘要 |
Disclosed are a stable recombinant cell clones which are stable in serum- and protein-free medium for at least 40 generations, a biomass obtained by multiplying the stable cell clone under serum- and protein-free culturing conditions, and a method of preparing recombinant proteins by means of the biomass. Furthermore, the invention relates to a method of recovering stable recombinant cell clones.
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申请公布号 |
US7094574(B2) |
申请公布日期 |
2006.08.22 |
申请号 |
US20050123362 |
申请日期 |
2005.05.06 |
申请人 |
BAXTER AKTIENGESELLSCHAFT |
发明人 |
REITER MANFRED;MUNDT WOLFGANG;DORNER FRIEDRICH |
分类号 |
C12N5/10;C12N5/00;C12N5/02;C12N5/08;C12N15/63;C12N15/85;C12P21/02 |
主分类号 |
C12N5/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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