| 发明名称 |
PYRIMIDINE COMPOUNDS HAVING TIE2 (TEK) INHIBITORY ACTIVITY |
| 摘要 |
<p>The invention relates to a compound of the Formula (I) or salt, prodrug or solvate thereof, wherein R<SUP>x</SUP>, R<SUP>y</SUP>, R<SUP>z</SUP>, R<SUP>5</SUP>, R<SUP>6</SUP>, A, B, L, n and m are as defined in the description. The invention also relates to pharmaceutical compositions of said compounds, the use of said compounds as medicaments and in the production of an anti-angiogenic effect in a warm blooded animal. The invention also relates to processes for the preparation of said compounds.</p> |
| 申请公布号 |
WO2006082371(A1) |
申请公布日期 |
2006.08.10 |
| 申请号 |
WO2006GB00272 |
申请日期 |
2006.01.27 |
| 申请人 |
ASTRAZENECA AB;ASTRAZENECA UK LIMITED;JONES, CLIFFORD, DAVID;LUKE, RICHARD WILLIAM ARTHUR;MCCOULL, WILLIAM |
发明人 |
JONES, CLIFFORD, DAVID;LUKE, RICHARD WILLIAM ARTHUR;MCCOULL, WILLIAM |
| 分类号 |
C07D413/12;A61K31/505;A61K31/506;A61P35/00;C07D239/42;C07D239/48;C07D403/12;C07D409/12 |
主分类号 |
C07D413/12 |
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