发明名称 |
AMYLOID ß PROTEIN AGGREGATION INHIBITOR, DIAGNOSTIC AGENT FOR ABNORMALITY OF AMYLOID ß PROTEIN, AND DIAGNOSTIC KIT FOR ABNORMALITY OF AMYLOID ß PROTEIN |
摘要 |
<p>Disclosed is an amyloid ß protein aggregation inhibitor. The inhibitor comprises a compound represented by the chemical structure composed of a monosaccharide or a sugar chain having two or more monosaccharides, wherein a part or all of the OH groups are substituted by (i) a sulfo group or a salt of a sulfo group and (ii) a hydrophobic group and a part or all of the remainder of the substituted OH groups may be substituted by a group selected from H, NH<SUB>2</SUB>, NHR<SUP>6</SUP> and NHR<SUP>6</SUP>R<SUP>7</SUP>. Particularly preferably, the inhibitor is a compound represented by the general formula (1).</p> |
申请公布号 |
WO2006083019(A1) |
申请公布日期 |
2006.08.10 |
申请号 |
WO2006JP302281 |
申请日期 |
2006.02.02 |
申请人 |
NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY;MIURA, YOSHIKO;KOIKE, MIHOKO;NISHIDA, YOSHIHIRO;KOBAYASHI, KAZUKIYO |
发明人 |
MIURA, YOSHIKO;KOIKE, MIHOKO;NISHIDA, YOSHIHIRO;KOBAYASHI, KAZUKIYO |
分类号 |
A61K31/7034;A61P25/28;A61P43/00;C07H15/203 |
主分类号 |
A61K31/7034 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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