发明名称 AMYLOID ß PROTEIN AGGREGATION INHIBITOR, DIAGNOSTIC AGENT FOR ABNORMALITY OF AMYLOID ß PROTEIN, AND DIAGNOSTIC KIT FOR ABNORMALITY OF AMYLOID ß PROTEIN
摘要 <p>Disclosed is an amyloid ß protein aggregation inhibitor. The inhibitor comprises a compound represented by the chemical structure composed of a monosaccharide or a sugar chain having two or more monosaccharides, wherein a part or all of the OH groups are substituted by (i) a sulfo group or a salt of a sulfo group and (ii) a hydrophobic group and a part or all of the remainder of the substituted OH groups may be substituted by a group selected from H, NH&lt;SUB&gt;2&lt;/SUB&gt;, NHR&lt;SUP&gt;6&lt;/SUP&gt; and NHR&lt;SUP&gt;6&lt;/SUP&gt;R&lt;SUP&gt;7&lt;/SUP&gt;. Particularly preferably, the inhibitor is a compound represented by the general formula (1).</p>
申请公布号 WO2006083019(A1) 申请公布日期 2006.08.10
申请号 WO2006JP302281 申请日期 2006.02.02
申请人 NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY;MIURA, YOSHIKO;KOIKE, MIHOKO;NISHIDA, YOSHIHIRO;KOBAYASHI, KAZUKIYO 发明人 MIURA, YOSHIKO;KOIKE, MIHOKO;NISHIDA, YOSHIHIRO;KOBAYASHI, KAZUKIYO
分类号 A61K31/7034;A61P25/28;A61P43/00;C07H15/203 主分类号 A61K31/7034
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