发明名称 |
Use of Vitamin D receptor activators or Vitamin D analogs to treat cardiovascular disease |
摘要 |
Disclosed are pharmaceutical compositions containing Vitamin D receptor activators or Vitamin D analogs to treat, prevent or inhibit vascular disease among other conditions. The pharmaceutical compositions may also include ACE inhibitors or other agents. Also disclosed are methods of reducing PAI-1 expression by administering effective amounts of Vitamin D receptor activators or Vitamin D analogs to a mammal in need thereof. Additionally disclosed are methods of preventing, inhibiting or treating thrombosis in a mammal in need of such prevention, inhibition or treatment comprising administering effective amounts of Vitamin D receptor activators or Vitamin D analogs to the mammal.
|
申请公布号 |
US2006171983(A1) |
申请公布日期 |
2006.08.03 |
申请号 |
US20050176103 |
申请日期 |
2005.07.07 |
申请人 |
TIAN JIN;MELNICK JOEL Z;TONER E S;WU-WONG JINSHYUN R;OSTROW DAVID H;WILLIAMS LAURA A;SUN EUGENE;KOMMALA DHEERENDRA R |
发明人 |
TIAN JIN;MELNICK JOEL Z.;TONER E. S.;WU-WONG JINSHYUN R.;OSTROW DAVID H.;WILLIAMS LAURA A.;SUN EUGENE;KOMMALA DHEERENDRA R. |
分类号 |
A61K31/59;A61F13/02;A61L15/16 |
主分类号 |
A61K31/59 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|